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Structural and Biochemical Characterization of the Cognate and ...

The thermodynamics and kinetics of the interaction of MazE9 with the functionally related mazEF6 operon indicate that the potential for intracellular cross-regulation is unlikely and the thermodynamic and kinetic parameters operational in its interaction with the promoter/operator region, specific to the maz EF9 operon are examined. The present study endeavors to decode the details of the ...

Insights into the solution structure and transcriptional regulation of ...

As mazE6 and mazE9 transcript levels were increased in the triple-mutant strain, we investigated whether MazF6 and MazF9 cleave mazE6 and mazE9 mRNA, respectively.

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Antitoxin MazE9. Gene. mazE9. Status. UniProtKB reviewed (Swiss-Prot) Organism. Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) Amino acids. 76 (go to sequence) Protein existence. Evidence at protein level. Annotation score. 3/5. Entry. Variant viewer. Feature viewer. Genomic coordinates. Publications. External links.

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MazE6 is a dimer in solution and harbors an RHH domain at the N-terminus similar to those observed for the homologous antitoxins, viz., MazE4, MazE7 and MazE9 despite a low sequence identity...

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Maze9 is a business consultancy and strategy coaching firm built to help small and midsize businesses address the challenges of sustainable growth. From identifying and resolving cash flow issues...