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Frontiers | TOX3 Promotes Ovarian Estrogen Synthesis: An RNA-Sequencing ...

In this study, we tested if overexpression of TOX3 is due to epigenetic factors that regulate TOX3/CASC16 expression in breast cancer cells. We identified hypomethylation of the TOX3 promoter as a significant contributor of TOX3 upregulation in luminal subtype breast cancer.

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Differential Epigenetic Regulation of TOX Subfamily High Mobility Group ...

Protocol. Specificity / Sensitivity. Tox3 Antibody recognizes endogenous levels of total Tox3 protein. This antibody does not cross-react with human Tox, Tox2, or Tox4 protein.

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TOX3 protein expression is correlated with pathological characteristics ...

TOX3 is a transcription factor expressed in the ventricular and subventricular zones. • TOX3 is expressed in radial glia and intermediate progenitors. • TOX3 co-localizes with Nestin, binds the Nestin promoter and increases its activity. • In utero electroporation of shRNAs against TOX3 at E12.5 reduces Nestin expression. •