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quenching endto--end cyclization (fqEEC) experiments or randomly along a polydisperse chain for fluorescence decay analysis with the Fluorescence Blob Model (FBM). The advantages and disadvantages of these two types of experiments are discussed as well as their range of applications and applicability to the field of protein folding.

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These experiments involve the labeling of a chain with dyes and quenchers either at the ends of a monodisperse chain for fluorescence quenching end-to-end cyclization (fqEEC) experiments or randomly along a polydisperse chain for fluorescence decay analysis with the fluorescence blob model (FBM).

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