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PDF Deciphering the Role of V88L Substitution in NDM-
Further analysis of the translated amino acid sequences of bla NDM-5 gene revealed that these point mutations resulted in the amino acid substitution involving non-active site residues viz., Valine-88-Leucine (V88L) and Methionine-154-Leucine (M154L).
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Figure 1 from Deciphering the Role of V88L ... - Semantic Scholar
This study characterizes the role of the V88L substitution in NDM-24 and provides insight about the NDM variants evolution. Keywords: New Delhi metallo-β-lactamase; NDM-24; kinetic profile ...
Proportions of various secondary structural elements in the NDM-1 ...
The NDM-5 variants were found harbouring V88L and M154L mutations. • The NDM variants were found harboring other antibiotic resistance markers, plasmid replicons and virulence genes. • It is essential to resolve the genetic insights of the evolving NDM variants for infection control and correct therapeutics